九州大学大学院医学研究院神経内科学教室

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ACTIVITY REPORT活動報告

研究業績

2011年度業績

  • Himeno E, Ohyagi Y, Ma L, Nakamura N, Miyoshi K, Sakae N, Motomura K, Soejima N, Yamasaki R, Hashimoto T, Tabira T, LaFerla FM, Kira J : Apomorphine treatment for Alzheimer’s mice promoting amyloid-β degradation. Ann Neurol 69 : 248-256, 2011.
  • Fang L*, Isobe N*, Yoshimura S, Yonekawa T, Matsushita T, Masaki K, Doi H, Ochi K, Miyamoto K, Kawano Y, Kira J : Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians. Neurology 76 : 2125-2127, 2011. *Equal contribution.
  • Matsuoka T, Suzuki SO, Suenaga T, Iwaki T, Kira J : Reappresal of aquaporin-4 astrocytopathy in Asian neuromyelitis optica and multiple sclerosis patients. Brain Pathol 21 : 516-532, 2011.
  • Matsuse D, Kitada M, Ogura F, Wakao S, Kohama M, Kira J, Tabata Y, Dezawa M : Combined transplantation of bone marrow stroma cell-derived neural progenitor cells with a collagen sponge and fibroblast growth factor releasing microspheres enhances recovery after cerebral ischemia in rats. Tissue Engineering 17 : 1993-2004, 2011.
  • Ma L, Ohyagi Y, Nakamura N, Iinuma KM, Miyoshi K, Himeno E, Soejima N, Yanagihara YT, Sakae N, Yamasaki R, Kira J : Activation of glutathione peroxidase and inhibition of p53-related apoptosis by apomorphine. J Alzheimer’s Disease 27 : 225-237, 2011.
  • Shinoda K, Matsushita T, Furuta K, Isobe N, Yonekawa T, Ohyagi Y, Kira J : Wall-eyed bilateral internuclear ophthalmoplegia (WEBINO) syndrome in a patient with Neuromyelitis optica spectrum disorder and anti-aquaporin-4 antibody. Mult Scler 17 : 885-887, 2011.
  • Ohshima S, Tsuboi Y, Yamamoto A, Kawakami M, Farrer MJ, Kira J, Shii H : Autonomic failures in Perry syndrome with DCTN1 mutation. Parkinsonism Relat Disord 16 : 612-614, 2010.
  • Kawamura N*, Piao H*, Minohara M, Matsushita T, Kusunoki S, Matsumoto H, Ikenaka K, Mizunoe Y, Kira J : Campylobacter jejuni DNA-binding protein from starved cells in Guillain-Barre syndrome. J Neuroimmunol 240-241 : 74-78, 2011. *Both contributed equally.
  • Piao H, Minohara M, Kawamura N, Li W, Matsushita T, Yamasaki R, Mizunoe Y, Kira J : Tissue binding patterns and in vitro effects of Campylobacter jejuni DNA-binding protein form starved cells. Neurochem Res 36 : 58-66, 2011.
  • Murai H, Yamashita N, Watanabe M, Nomura Y, Motomura M, Yoshikawa H, Kawaguchi N, Onodera H, Araga S, Isobe N, Nakamura Y, Nagai M, Kira J : Characteristics of myasthenia gravis according to onset-age : Japanese nationwide survey. J Neurol Sci 305 : 97-102, 2011.
  • Pineda AAM*, Minohara M*, Kawamura N, Matsushita T, Yamasaki R, Sun X, Piao H, Shimokawa H, Kira J : Preventive and therapeutic effects of the selective Rho-kinase inhibitor fasudil on experimental autoimmune neuritis. J Neurol Sci 306 : 115-120, 2011. *Equal contribution.
  • Uehara T, Murai H, Yamasaki R, Kikuchi H, Shigeto H, Ohyagi Y, Kira J : Thymoma-associated progressive encephalomyelitis with rigidity and myoclonus successfully treated with thymectomy and intravenous immunoglobulin. Eur Neurol 66 : 328-330, 2011.
  • Doi H, Arimura K, Ohyagi Y, Kira J : Frostbite-like skin lesion as an autonomic symptom in Isaacs’ syndrome. Intern Med 50 : 1113-1115, 2011.
  • Doi H, Matsushita T, Isobe N, Tateishi T, Kira J : Analysis of cerebrospinal fluid cytokines and growth factors in multiple sclerosis patients with and without chronic headaches. Neurology Asia 16 : 65-70, 2011.
  • Shigetou H, Sakata A, Morioka T, Takase K, Hagiwara H, Kamada T, Kanamori Y, Hashiguchi K, Tobimatsu S, Yamashita N, Kira J : Peri-orbital electrodes as a supplemental recording for detection of ictal discharges in medial temporal lobe epilepsy. Neurology Asia 16 : 303-307, 2011.
  • Yonekawa T, Matsushita T, Minohara M, Isobe N, Masaki K, Yoshimura S, Nishimura S, Kira J : T cell reactivities to myelin protein-derived peptides in neuromyelitis optica patients with anti-aquaporin-4 antibody. Neurology Asia. 16 : 139-142, 2011.
  • Takase K, Shigeto H, Furuta K, Sakae N, Ohyagi Y, Kira J : Transient vocal cord palsy caused by hypoperfusion of unilateral hemisphere. Fukuoka Acta Med 102 : 273-276, 2011.
  • 稲葉明子、鳥居孝子、篠田紘司、山﨑亮、大八木保政、吉良潤一：胃全摘出後23年後に末梢神経障害、脊髄症、小脳失調、潜在的視神経症を呈した銅欠症１例．臨床神経 51 : 412-416, 2011.
  • 上田麻紀、河村信利、立石貴久、重藤寛史、大八木保政、吉良潤一：後天性vonWillebrand 症候群を伴った慢性炎症性脱髄性多発根ニューロパチーの１例．臨床神経 51 : 334-337, 2011.
  • 緒方英紀、重藤寛史、鳥居孝子、河村信利、大八木保政、吉良潤一：梅毒性視神経炎に合併したCharles-Bonnet 症候群の一例．臨床神経 51 : 595-598, 2011
  • Kira J : Astrocytopathy in Balo’s disease. Mult Scler 17 : 771-779, 2011.
  • Kira J : Autoimmunity in neuromyelitis optica and opticospinal multiple sclerosis : astrocytopathy as a common denominator in demyelinating disorders. J Neurol Sci 311 : 69-77, 2011.
  • Kira J : Neuromyelitis optica and opticospinal multiple sclerosis : Mechanisms and pathogenesis. Pathophysiology 18 : 69-79, 2011.
  • 吉良潤一：ガイドラインに基づいた多発性硬化症治療．日本医事新報 4548 : 75-81, 2011.
  • 吉良潤一：多発性硬化症治療ガイドライン2010．メディカル朝日 40 : 78-81, 2011.
  • 吉良潤一：神経免疫疾患研究の将来展望. 学術の動向 7 : 66-72, 2011.
  • 吉良潤一：HAM．今日の治療指針2011年版―私はこう治療している―山口徹、北原光夫、稲井次夫（編）． 医学書院 pp. 830-831, 2011.
  • 吉良潤一：新刊書評．難病患者さんやご家族への熱い思い．久保裕男さんの著書『MSWハンドブック- 難病相談・支援を通して-』難病と在宅ケア 16 : 31, 2011.
  • 吉村怜、吉良潤一：多発性硬化症の疫学―全国臨床疫学調査からみえてきたもの．医学のあゆみ 237 : 284-290, 2011.
  • 山下謙一郎、吉良潤一：日本人の認知症の特徴と疫学．臨牀と研究 88 : 649-652, 2011.
  • 松下拓也、眞﨑勝久、鈴木諭、松岡健、米川智、呉暁牧、岩城徹、吉良潤一：視神経脊髄炎、多発性硬化症、Balo病におけるアストロサイト障害の特徴．臨床神経 51 : 898-900, 2011.
  • 松下拓也、吉良潤一：多発性硬化症―治療の現状と展望．日本臨牀 69 : 2077-2086, 2011.
  • 松下拓也：脱髄疾患の治療の進歩．神経治療学 28: 355-361, 2011.
  • 古谷博和：進行性骨化性線維異形成症（FOP）の病態と治療への試み．医療 65 : 193-198, 2011.
  • 大八木保政：認知症の症状・診断基準と重症度評価：アルツハイマー型認知症．臨床と研究 88 : 653-656, 2011.
  • 大八木保政：細胞内アミロイド・および酸化ストレスを標的とする治療薬：アポモルフィン．臨床神経 51 : 884-887, 2011.
  • 大八木保政：認知症の新規治療と地域ネットワークの構築～認知症疾患医療センターの立場から．筑紫医師会報 36 : 31-35, 2011.
  • 岩下宏：続・日本人の発見した神経疾患クロウ・深瀬症候群（POEMS 症候群）．BRAIN and NERVE 63 : 131-139, 2011.

過去の業績

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